Saturday 28 June 2014

And it Stoned Me...


Let's not forget about the drugs!  Seems apt for a Glasto. weekend.  As a trained pharmaceutical scientist, I can firmly attest the more the merrier. Prescribed only of course.
My favourite at the moment is Venlafaxine.  At first I took one a day but it wasn't enough. Was on 3 a day for a few years but have gone back down to 1 a day which allows me to get through a day of work without crying (Bonus! Never a great look in the Stairwell of Tears, which is like the Bench of Tears on Eastenders but grimmer surroundings).


Venlafaxine, or (R/S)-1-[2-dimethylamino-1-(4-methoxyphenyl)-ethyl]cyclohexanol as it is known to it's friends, is an anti-depressant but has another advantage in that it reduces hot flushes. I was always good at those before my illness but now when one comes upon me I really do NEED to fling clothes off immediately. At least I can mostly manage to curb that impulse as required.

Only just had a look at the potential side effects on Wikipedia - let's hope they're wrong about a few of these, which include:
  • Headache — an often transient side effect that is common to most serotonin reuptake inhibitors and that most often occurs at the beginning of therapy or after a dose escalation.
  • Nausea — an adverse effect that is more common with venlafaxine than with the SSRIs. Usually transient and less severe in those receiving the extended release formulations - oh, so that's alright then.
  • Insomnia
  • Asthenia (weakness)
  • Dizziness
  • Ejaculation disorder
  • Somnolence
  • Dry mouth
  • Sweating
  • Constipation
  • Nervousness
  • Abnormal vision
  • Anorgasmia
  • Hypertension
  • Impotence
  • Paresthesia
  • Tremor
  • Vasodilation
  • Vomiting
  • Weight loss/gain
  • Chills
  • Palpitations
  • Confusion
  • Depersonalisation
  • Night sweats
  • Menstrual disorders associated with increased bleeding or increased irregular bleeding (e.g. menorrhagia, metrorrhagia)
  • Urinary frequency increased
  • Abnormal dreams
  • Decreased libido
  • Increased muscle tonus
  • Yawning
  • Abnormality of accommodation
  • Abnormal ejaculation/orgasm (males)
  • Urinary hesitancy
  • Serum cholesterol increased (especially when treatment is prolonged and it may be dose-dependent)
So sweating, chills, weight loss and gain, depersonalisation (no personality?) Well, that explains me then.............

Have a great weekend everybody

K xx


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